UNMC Bioinformatics and Molecular Modeling Facility
 
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Educational Resources

Previous Courses

Introduction to Computational Molecular Biology 
(PHSC 820, BIOC 940, PAMM 950B)
This 2-credit course provides the basic knowledge and skills needed for the practical use of the Bioinformatics and Molecular Modeling Tools(Coordinators: Simon Sherman, Nora Chapman, Bill Chaney, UNMC)
Introduction to Bioinformatics
(PAMM 950, ISQA 4000, ISQA 8080, CSCI 4980)

This 2-credit course provides a survey of the area of bioInformatics, which is a combination of molecular biology, genomics, and the use of computers to process, analyze, store, and retrieve biological information. This class will combine lectures in the subjects of molecular biology, computer science, and information science.  (Coordinators: Dr. Donald Johnson, UNMC and Dr. Justin Stolen, UNO)

Selected Topics: Computational Chemistry and Molecular Modeling

This course is intended to familiarize students with some aspects of the computational chemistry and molecular modeling techniques that may be used to address various problems related to properties of molecules. (Instructor: Simon Sherman, UNMC)

Computer Aided Genetic Sequence Analysis Emphasizes primarily the hands-on aspect of running the programs, but with about half the lectures covering aspects of the theory behind the sequence analysis programs, and the interpretation of the program results where these results can be ambiguous. (Instructors: Nora Chapman, Bill Chaney, Eric Haas, UNMC)
SeqLab (GCG's graphical interface) An introduction to the user interface. Specific programs are only covered as examples. Web-based material for this is currently limited to that included in the GCG User Manual. (Instructor: Eric Haas, UNMC)
Unix An introduction for molecular biologists to file and directory management and printing. (Instructor: Eric Haas, UNMC)
Algorithms in biological sequence analysis. This course is about algorithms used in the manipulation and analysis of biological sequence data, which may be regarded as strings from a four symbol alphabet (in the case of DNA), or a twenty symbol alphabet (in the case of proteins). (Instructor: David Jaffe, UNL)
Special Topics: Computational Molecular Biology. This course will review current computational approaches to problems in molecular biology. This course is a companion to one being taught by David Jaffe in the Math Dept. (see http://www.math.unl.edu/~djaffe/bio.html for more information). As such, our course will cover different biological problems and/or different computational approaches than his, while still strongly emphasizing the biological context of each problem. Potential topics include, but are not limited to: Comparing multiple DNA sequences at once, DNA mapping, phylogenetic trees, genome rearrangements, protein structure prediction, protein function prediction, and probabilistic modeling of data. We will study algorithmic approaches to the problems we cover as well as approaches rooted in machine learning, probability, and statistics, e.g. hidden Markov models, genetic algorithms, and neural networks. (Instructors: Stephen Scott, Jitender Deogun, UNL)

Nomenclature

IUPAC International Union of Pure and Applied Chemistry
AAnP IUPAC-IUBMB nomenclature for amino acids and peptides
Carbohydrates IUPAC-IUBMB nomenclature for carbohydrates
JCBN IUPAC-IUB Joint commission on Biochemical Nomenclature (JCBN)
Abbreviations of chemical compounds
List of nomenclature related references for proteins from SWISS-PROT
HUGO Human Gene Nomenclature Committee 
NCBI Taxonomy database contains the names of all organisms that are represented in the genetic databases with at least one nucleotide or protein sequence
BIOSIS Taxonomy & Nomenclature
Genetic code Viewer Genetic code viewer at EBI

Dictionaries

Glossary Computational Chemistry And Molecular Modeling
DCB Dictionary of cell biology by Julian Dow

Online Courses, Tutorials, and Hyperlinks

Introduction to Computational Molecular Biology

To provide the basic knowledge and skills needed for the practical use of the Bioinformatics and Molecular Modeling Tools (UNMC)
Biocomputing courses resource list Syllabi for a variety of courses and tutorials on Bioinformatics (from VSNS BCD)
List of BioInformatics Courses from the Rockefeller University
University Bioinformatics Programs from BioTech server at Indiana University
Biocomputing tutorials EMBnet Biocomputing tutorials
BioComputing Hypertext Coursebook from VSNS BCD
Homology modelling course from the EMBL
Tutorial on secondary structure prediction from Harry Mangalam / UC Irvine
Introduction to Glycolysis from Leeds University
Amino acid properties Physico and chemical information on amino acids
Amino acids 2 An information page on amino acids (from Berlin Free Univ.)